BEBPA conferences include 3 days of presentations, workshops and round-table discussions on topics of current interest to the analytical biopharmaceutical community. It is hoped that these presentations and discussions will provide topics for future white paper working groups.
2025 HCP Speaker Abstracts
Suggested Topics:
- HCPs that degrade polysorbate or other excipients
- Single- or multi-protein ELISAs
- MS methods
- Enzymatic methods
- HCP that degrade the product (proteases, glycosidases, etc.)
- HCP ELISA coverage assessment methods
- Animal immunization strategies for HCP ELISA antibody generation
- Bioprocessing Topics
- Affinity ligands for HCP removal
- Depth filtration
- Membrane vs. chromatographic purification
- HCPs in continuous processing
- Engineering mAbs to reduce HCP hitchhikers
- Engineering cell lines to reduce HCP problems
- Aggregates and HCPs
- Do HCP considerations affect upstream process decisions?
- Case Studies
- HCPs in biosimilars
- HCPs in engineered fusion proteins
- HCPs in gene therapy products
- New Modalities
- What methods and strategies are being used?
- Regulatory perspectives
- Risk Assessment
- Use of in silico vs. in vitro vs. in vivo methods to assess immunogenicity
- Importance of individual proteins to patient health
- Adding Immunoassays for specific HCPs
- Alternatives to conventional ELISA and MS analysis
- Non-immunoassay methods for monitoring individual HCPs in early stage vs. release
- Laboratory automation for ELISA and MS
- Mass spectrometry as a release assay in late stage
- Comparability best practices for HCP
- Quantitative MS methods
- HCP ELISA troubleshooting
Hotel Information
Discounted hotel information coming soon.
Rikli Balance Hotel
Cankarjeva cesta 4,
4260 Bled, Slovenia
Telephone: +386 4 579 1700
Website: Rikli Balance Hotel
